Takayasu aortitis with acute dissection and hemopericardium

Fabio Tavora, Jean Jeudy, Christopher Gocke, Allen Burke

Research output: Contribution to journalArticlepeer-review


We report a case of a 57-year-old woman with an unremarkable past medical history who presented to the emergency department with maxillary pain that later radiated to the chest. She died less than 12 h after admission. CT findings were consistent with ascending aorta dissection with hemopericardium. Autopsy revealed a tear immediately proximal to the ostium of the brachiocephalic artery and a dissecting flap with false lumen, rupture, and hemopericardium. Histologically, there was a zonal medial necrosis with surrounding chronic inflammation, focal destruction of the media, and fibrosis of the intima and adventitia. A diagnosis of granulomatous necrotizing aortitis of Takayasu type was made. This case demonstrates a rare example of aortitis underlying aortic dissection and emphasizes the need for careful histologic examination in cases of aortic root disease.

Original languageEnglish (US)
Pages (from-to)320-323
Number of pages4
JournalCardiovascular Pathology
Issue number6
StatePublished - Nov 1 2005
Externally publishedYes


  • Aortic dissection
  • Aortitis
  • Takayasu

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cardiology and Cardiovascular Medicine

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