Tailored strategies for radiation therapy in classical Hodgkin's lymphoma

Stephanie A. Terezakis, Yvette L. Kasamon

Research output: Contribution to journalReview articlepeer-review

Abstract

Radiotherapeutic advances have contributed to the evolution of Hodgkin's lymphoma (HL) treatment paradigms. A reduction in radiation therapy (RT) field size and dose has the potential to significantly impact the therapeutic ratio by diminishing late toxicities while maintaining curability. Substantial progress in risk stratification has contributed to the development of tailored RT strategies which address both field design as well as dose. Technologic improvements have also enhanced the ability to adapt the RT technique to the individual patient. The refinement of the RT approach and its incorporation into current combined modality strategies in adult classical HL is the subject of ongoing investigation and is critically reviewed.

Original languageEnglish (US)
Pages (from-to)71-84
Number of pages14
JournalCritical Reviews in Oncology/Hematology
Volume84
Issue number1
DOIs
StatePublished - Oct 1 2012

Keywords

  • Hodgkin's lymphoma
  • Involved-field radiation therapy
  • Late effects
  • Radiation

ASJC Scopus subject areas

  • Hematology
  • Oncology

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