TY - JOUR
T1 - Taenia solium infection in a rural community in the Peruvian Andes
AU - Moro, P. L.
AU - Lopera, L.
AU - Bonifacio, N.
AU - Gilman, R. H.
AU - Silva, B.
AU - Verastegui, M.
AU - Gonzales, A.
AU - Garcia, H. H.
AU - Cabrera, L.
AU - Pretell, J.
AU - Tovar, M.
AU - Gonzalez, A.
AU - Gavidia, C.
AU - Falcon, N.
AU - Bernal, T.
AU - Herrera, G.
AU - Jimenez, J.
AU - Rodriguez, S.
AU - Tsang, C. W.
PY - 2003/6
Y1 - 2003/6
N2 - An epidemiological study was conducted in a highland, rural community, in Peru, to determine the seroprevalences of human and porcine infection with Taenia solium and the risk factors associated with human infection. The seroprevalences, determined using an assay based on enzyme-linked-immuno-electrotransfer blots (EITB), were 21% (66/316) in the humans and 65% (32/49) in the pigs. The human subjects aged < 30 years were more likely to be positive for anti-T. solium antibodies than the older subjects (P < 0.001). The risk factors associated with human seropositivity were lack of education beyond the elementary level [odds ratio (OR) = 2.69; 95% confidence interval (CI) = 1.09-6.65] and pig-raising (OR = 1.68; CI = 0.96-2.92). Curiously, sheep-raising was inversely associated with human T. solium infection (OR = 0.50; CI = 0.28-0.90). The study site appears to be a new endemic focus for T. solium in the central Peruvian Andes. Although, in earlier studies, the seroprevalence of T. solium infection has generally been found to increase with age, the opposite trend was observed in the present study. The results of follow-up studies should help determine if the relatively high seroprevalence in the young subjects of the present study is the result of a transient antibody response.
AB - An epidemiological study was conducted in a highland, rural community, in Peru, to determine the seroprevalences of human and porcine infection with Taenia solium and the risk factors associated with human infection. The seroprevalences, determined using an assay based on enzyme-linked-immuno-electrotransfer blots (EITB), were 21% (66/316) in the humans and 65% (32/49) in the pigs. The human subjects aged < 30 years were more likely to be positive for anti-T. solium antibodies than the older subjects (P < 0.001). The risk factors associated with human seropositivity were lack of education beyond the elementary level [odds ratio (OR) = 2.69; 95% confidence interval (CI) = 1.09-6.65] and pig-raising (OR = 1.68; CI = 0.96-2.92). Curiously, sheep-raising was inversely associated with human T. solium infection (OR = 0.50; CI = 0.28-0.90). The study site appears to be a new endemic focus for T. solium in the central Peruvian Andes. Although, in earlier studies, the seroprevalence of T. solium infection has generally been found to increase with age, the opposite trend was observed in the present study. The results of follow-up studies should help determine if the relatively high seroprevalence in the young subjects of the present study is the result of a transient antibody response.
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U2 - 10.1179/000349803235002371
DO - 10.1179/000349803235002371
M3 - Article
C2 - 12831523
AN - SCOPUS:0037561415
SN - 0003-4983
VL - 97
SP - 373
EP - 379
JO - Annals of Tropical Medicine and Parasitology
JF - Annals of Tropical Medicine and Parasitology
IS - 4
ER -