@article{476de195e0ad4d5681cad8061c69cb83,
title = "T-cell immunotherapy: Looking forward",
abstract = "The rapidly expanding field of T-cell immunotherapy has experienced clinical successes along with some serious toxicities. {"}T Cell Immunotherapy: Optimizing Trial Design,{"} a workshop sponsored by the National Institutes of Health's (NIH's) Office of Biotechnology Activities (OBA), brought together researchers to discuss the scientific advances and share new data on key trial design issues, including the selection of new targets, optimizing the T-cell population, preconditioning regimens, strategies to promote persistence of cells, and analysis and management of acute reactions to T-cell infusions with the goal of identifying best practices and a research agenda that will facilitate further development and maximize the safety of this promising approach.",
author = "Jacqueline Corrigan-Curay and Kiem, {Hans Peter} and David Baltimore and Marina O'Reilly and Brentjens, {Renier J.} and Laurence Cooper and Stephen Forman and Stephen Gottschalk and Philip Greenberg and Richard Junghans and Helen Heslop and Michael Jensen and Crystal Mackall and Carl June and Oliver Press and Daniel Powell and Antoni Ribas and Steven Rosenberg and Michel Sadelain and Brian Till and Patterson, {Amy P.} and Jambou, {Robert C.} and Eugene Rosenthal and Linda Gargiulo and Maureen Montgomery and Kohn, {Donald B.}",
note = "Funding Information: S.G.{\textquoteright}s institution has research collaborations with Celgene Corporation and bluebird bio. He has been funded by the DANA Foundation, the James S. McDonnell Foundation, and Cancer Prevention Research Institute Texas grant RP101335. H.H. and S.F. are supported by grants P01CA094237, P50CA126752, and U54HL08100 from the NIH and a SCOR award from the Leukemia and Lymphoma Society. Funding Information: C.J. has sponsored research support from No-vartis through a grant that supports research in the field of CARs for oncology. He also has intellectual property in the area of adoptive cell therapy that is owned by the University of Pennsylvania and the US government. This has been licensed to Novartis. Both the university and C.J. may receive royalties; this arrangement is managed in accordance with the University of Pennsylvania policies and oversight.",
year = "2014",
month = sep,
doi = "10.1038/mt.2014.148",
language = "English (US)",
volume = "22",
pages = "1564--1574",
journal = "Molecular Therapy",
issn = "1525-0016",
publisher = "Nature Publishing Group",
number = "9",
}