T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors

Ahmad R. Sedaghat, Darius A. Rastegar, Karen A. OConnell, Jason B. Dinoso, Claus O. Wilke, Joel N. Blankson

Research output: Contribution to journalArticle

Abstract

Elite controllers or suppressors are untreated human immunodeficiency virus type 1 (HIV-1)-infected patients who maintain undetectable viral loads. In this study, we show that most elite suppressors do not experience significant changes in T cell counts over a 10-year period. Interestingly, treatment of an elite suppressor with highly active antiretroviral therapy (HAART) led to a marked decrease in immune activation.

Original languageEnglish (US)
Pages (from-to)1763-1766
Number of pages4
JournalClinical Infectious Diseases
Volume49
Issue number11
DOIs
StatePublished - Dec 1 2009

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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