Systems biology of polycystic kidney disease: A critical review

Luis Fernando Menezes, Gregory G. Germino

Research output: Contribution to journalArticle

Abstract

The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

Original languageEnglish (US)
Pages (from-to)39-52
Number of pages14
JournalWiley Interdisciplinary Reviews: Systems Biology and Medicine
Volume7
Issue number1
DOIs
StatePublished - Jan 1 2015

Fingerprint

Polycystic Kidney Diseases
Systems Biology
Cysts
Costs and Cost Analysis
Costs

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Medicine (miscellaneous)

Cite this

Systems biology of polycystic kidney disease : A critical review. / Menezes, Luis Fernando; Germino, Gregory G.

In: Wiley Interdisciplinary Reviews: Systems Biology and Medicine, Vol. 7, No. 1, 01.01.2015, p. 39-52.

Research output: Contribution to journalArticle

Menezes, Luis Fernando ; Germino, Gregory G. / Systems biology of polycystic kidney disease : A critical review. In: Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 2015 ; Vol. 7, No. 1. pp. 39-52.
@article{37600b8257bc4c71856d16db5159a7c5,
title = "Systems biology of polycystic kidney disease: A critical review",
abstract = "The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.",
author = "Menezes, {Luis Fernando} and Germino, {Gregory G.}",
year = "2015",
month = "1",
day = "1",
doi = "10.1002/wsbm.1289",
language = "English (US)",
volume = "7",
pages = "39--52",
journal = "Wiley Interdisciplinary Reviews: Systems Biology and Medicine",
issn = "1939-5094",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

TY - JOUR

T1 - Systems biology of polycystic kidney disease

T2 - A critical review

AU - Menezes, Luis Fernando

AU - Germino, Gregory G.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

AB - The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

UR - http://www.scopus.com/inward/record.url?scp=84923205995&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923205995&partnerID=8YFLogxK

U2 - 10.1002/wsbm.1289

DO - 10.1002/wsbm.1289

M3 - Article

C2 - 25641951

AN - SCOPUS:84923205995

VL - 7

SP - 39

EP - 52

JO - Wiley Interdisciplinary Reviews: Systems Biology and Medicine

JF - Wiley Interdisciplinary Reviews: Systems Biology and Medicine

SN - 1939-5094

IS - 1

ER -