Systems approaches to cancer biology

Tenley C. Archer, Elana J. Fertig, Sara J.C. Gosline, Marc Hafner, Shannon K. Hughes, Brian A. Joughin, Aaron S. Meyer, Stephen R. Piccolo, Ayesha N. Shajahan-Haq

Research output: Contribution to journalArticle

Abstract

Cancer systems biology aims to understand cancer as an integrated system of genes, proteins, networks, and interactions rather than an entity of isolated molecular and cellular components. The inaugural Systems Approaches to Cancer Biology Conference, cosponsored by the Association of Early Career Cancer Systems Biologists and the National Cancer Institute of the NIH, focused on the interdisciplinary field of cancer systems biology and the challenging cancer questions that are best addressed through the combination of experimental and computational analyses. Attendees found that elucidating the many molecular features of cancer inevitably reveals new forms of complexity and concluded that ensuring the reproducibility and impact of cancer systems biology studies will require widespread method and data sharing and, ultimately, the translation of important findings to the clinic.

Original languageEnglish (US)
Pages (from-to)6774-6777
Number of pages4
JournalCancer Research
Volume76
Issue number23
DOIs
StatePublished - Dec 1 2016

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Archer, T. C., Fertig, E. J., Gosline, S. J. C., Hafner, M., Hughes, S. K., Joughin, B. A., Meyer, A. S., Piccolo, S. R., & Shajahan-Haq, A. N. (2016). Systems approaches to cancer biology. Cancer Research, 76(23), 6774-6777. https://doi.org/10.1158/0008-5472.CAN-16-1580