Systemic treatment of cancer with low and safe levels of radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies

Over the past century, there have been many attempts to diagnose and treat cancer with electromagnetic elds. While the use of high energy ionizing radiation has become a mainstay in the diagnosis (x-ray and computed tomography) and treatment (radiation therapy) of cancer, the use of low intensity, nonionizing electromagnetic elds is much less common.1 More than two decades ago, we pioneered the use of low and safe levels of radiofrequency electromagnetic elds (RF EMF) in the treatment of insomnia.2 Our original hypothesis was that administration of low and safe levels of electromagnetic elds by means of an antenna placed inside the mouth cavity would allow for safe delivery to the brain.2 Experiments conducted in healthy subjects in the United States3 and Switzerland4 demonstrated that a single modulation frequency (42.7 Hz) had a sleep inducing effect in healthy individuals. We tested the hypothesis that amplitude modulation of a carrier frequency such as 27.12 MHz, which is approved worldwide for medical use, could be used therapeutically for the treatment of sleep disorders and demonstrated that such an approach was both feasible and effective for the treatment of chronic insomnia.5.