TY - JOUR
T1 - Systemic Therapy for Squamous Cell Carcinoma of the Head and Neck
AU - Pancari, Philip
AU - Mehra, Ranee
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - The use of systemic therapy as part of curative treatment and palliation is an evolving paradigm for squamous cell cancer of the head and neck (SCCHN), which historically has been treated with local modalities. At present, the treatment armamentarium includes traditional cytotoxic therapy, targeted biological agents, and emerging immunotherapeutics. This article discusses the use of all of these systemic approaches for the curative and palliative treatment of SCCHN.
AB - The use of systemic therapy as part of curative treatment and palliation is an evolving paradigm for squamous cell cancer of the head and neck (SCCHN), which historically has been treated with local modalities. At present, the treatment armamentarium includes traditional cytotoxic therapy, targeted biological agents, and emerging immunotherapeutics. This article discusses the use of all of these systemic approaches for the curative and palliative treatment of SCCHN.
KW - Chemoradiation
KW - Epidermal growth factor receptor
KW - Platinum chemotherapy
KW - Squamous cell head and neck cancer
UR - http://www.scopus.com/inward/record.url?scp=84929324557&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929324557&partnerID=8YFLogxK
U2 - 10.1016/j.soc.2015.03.004
DO - 10.1016/j.soc.2015.03.004
M3 - Review article
C2 - 25979393
AN - SCOPUS:84929324557
SN - 1055-3207
VL - 24
SP - 437
EP - 454
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 3
ER -