TY - JOUR
T1 - Systematic review of factors associated with depression and anxiety disorders among older adults with Parkinson's disease
AU - Sagna, Atami
AU - Gallo, Joseph J.
AU - Pontone, Gregory M.
PY - 2014/7
Y1 - 2014/7
N2 - Depression and anxiety disorders have a substantial impact on the quality of life, the functioning and mortality of older adults with Parkinson's disease (PD). The purpose of this systematic review was to examine the factors associated with the prevalence of depression and anxiety disorders among individuals with PD aged 60 years and older. Following a literature search in PubMed, PsycINFO, CINAHL, and EMBASE, 5 articles met the inclusion criteria (adults aged 60 years and older, individuals with PD, and with depression and anxiety disorders, and English-language peer reviewed articles) and were included in this review. These studies were conducted in the U.S (n=3), in Italy (n=1) and the U.K (n=1). Findings indicated that autonomic symptoms, motor fluctuations, severity and frequency of symptoms, staging of the disease, and PD onset and duration were associated with the prevalence of depression and anxiety disorders among older adults suffering from PD. Despite the limited number of studies included in the review, depression and anxiety disorders are often unrecognized and untreated and the comorbidity greatly exacerbates PD symptoms. The identification of factors associated with the development of depression and anxiety disorders could help in designing preventive interventions that would decrease the risk and burden of depression and anxiety disorders among older adults with PD.
AB - Depression and anxiety disorders have a substantial impact on the quality of life, the functioning and mortality of older adults with Parkinson's disease (PD). The purpose of this systematic review was to examine the factors associated with the prevalence of depression and anxiety disorders among individuals with PD aged 60 years and older. Following a literature search in PubMed, PsycINFO, CINAHL, and EMBASE, 5 articles met the inclusion criteria (adults aged 60 years and older, individuals with PD, and with depression and anxiety disorders, and English-language peer reviewed articles) and were included in this review. These studies were conducted in the U.S (n=3), in Italy (n=1) and the U.K (n=1). Findings indicated that autonomic symptoms, motor fluctuations, severity and frequency of symptoms, staging of the disease, and PD onset and duration were associated with the prevalence of depression and anxiety disorders among older adults suffering from PD. Despite the limited number of studies included in the review, depression and anxiety disorders are often unrecognized and untreated and the comorbidity greatly exacerbates PD symptoms. The identification of factors associated with the development of depression and anxiety disorders could help in designing preventive interventions that would decrease the risk and burden of depression and anxiety disorders among older adults with PD.
KW - Anxiety disorders
KW - Depression
KW - Factors
KW - Older adults
KW - Parkinson's disease
KW - Systematic review
UR - http://www.scopus.com/inward/record.url?scp=84902357778&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902357778&partnerID=8YFLogxK
U2 - 10.1016/j.parkreldis.2014.03.020
DO - 10.1016/j.parkreldis.2014.03.020
M3 - Review article
C2 - 24780824
AN - SCOPUS:84902357778
SN - 1353-8020
VL - 20
SP - 708
EP - 715
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
IS - 7
ER -