Systematic review of catheter-based intra-arterial therapies in hepatocellular carcinoma: State of the art and future directions

R. Duran, J. Chapiro, R. E. Schernthaner, J. F.H. Geschwind

Research output: Contribution to journalReview article

Abstract

Intra-arterial therapies (IATs) play a pivotal role in the management of patients with primary and secondary liver malignancies. The unique advantages of these treatments are their ability to selectively deliver a high dose of anticancer treatment while preserving healthy liver tissue. The proven efficacy of these catheter-based locoregional therapies in a highly systemic chemoresistant cancer such as hepatocellular carcinoma (HCC), along with the minimally invasive nature of these treatments, quickly yielded wide acceptance in themedical community and revolutionized the field of Interventional Oncology. In this article, we describe the clinical rationale and background of catheter-based IATs.We provide an overview of clinical achievements of these treatments alone and in combination with sorafenib in patients with HCC.

Original languageEnglish (US)
Article number20140564
JournalBritish Journal of Radiology
Volume88
Issue number1052
DOIs
StatePublished - Aug 1 2015

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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