System identification for motion of proteins using an AFM-based nanorobotic manipulation

Jungyul Park, Deok Ho Kim, Byungkyu Kim, Kyo Il Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In biomanipulation research area, the reliable force measurement and modeling of biological molecules are essential techniques to estimate the material properties and a motion of the biological molecule. In this study, we introduce the system identification method to estimate motion of protein and material characteristics using AFM-based nanorobotic manipulation. Modeling of piezoresistive AFM cantilever and equivalent model for force-measurement system are presented. Based on equivalent, dynamic motion of a protein is efficiently estimated in real-time. In case of globular protein, damping coefficient and spring constant show good agreement between estimation results and actual values.

Original languageEnglish (US)
Title of host publication2003 Nanotechnology Conference and Trade Show - Nanotech 2003
EditorsM. Laudon, B. Romanowicz
Pages392-395
Number of pages4
StatePublished - 2003
Externally publishedYes
Event2003 Nanotechnology Conference and Trade Show - Nanotech 2003 - San Francisco, CA, United States
Duration: Feb 23 2003Feb 27 2003

Publication series

Name2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Volume3

Conference

Conference2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Country/TerritoryUnited States
CitySan Francisco, CA
Period2/23/032/27/03

Keywords

  • Force sensing
  • Nanorobotic manipulation
  • Protein
  • System identification

ASJC Scopus subject areas

  • Engineering(all)

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