System identification for motion of proteins using an AFM-based nanorobotic manipulation

Jungyul Park; Deok Ho Kim; Byungkyu Kim; Kyo Il Lee

System identification for motion of proteins using an AFM-based nanorobotic manipulation

Jungyul Park, Deok Ho Kim, Byungkyu Kim, Kyo Il Lee

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In biomanipulation research area, the reliable force measurement and modeling of biological molecules are essential techniques to estimate the material properties and a motion of the biological molecule. In this study, we introduce the system identification method to estimate motion of protein and material characteristics using AFM-based nanorobotic manipulation. Modeling of piezoresistive AFM cantilever and equivalent model for force-measurement system are presented. Based on equivalent, dynamic motion of a protein is efficiently estimated in real-time. In case of globular protein, damping coefficient and spring constant show good agreement between estimation results and actual values.

Original language	English (US)
Title of host publication	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Editors	M. Laudon, B. Romanowicz
Pages	558-561
Number of pages	4
State	Published - 2003
Externally published	Yes
Event	2003 Nanotechnology Conference and Trade Show - Nanotech 2003 - San Francisco, CA, United States Duration: Feb 23 2003 → Feb 27 2003

Publication series

Name	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Volume	2

Conference

Conference	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Country/Territory	United States
City	San Francisco, CA
Period	2/23/03 → 2/27/03

Keywords

Force sensing
Nanorobotic Manipulation
Protein
System identification

ASJC Scopus subject areas

General Engineering

Cite this

System identification for motion of proteins using an AFM-based nanorobotic manipulation. / Park, Jungyul; Kim, Deok Ho; Kim, Byungkyu et al.
2003 Nanotechnology Conference and Trade Show - Nanotech 2003. ed. / M. Laudon; B. Romanowicz. 2003. p. 558-561 (2003 Nanotechnology Conference and Trade Show - Nanotech 2003; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Park, J, Kim, DH, Kim, B & Lee, KI 2003, System identification for motion of proteins using an AFM-based nanorobotic manipulation. in M Laudon & B Romanowicz (eds), 2003 Nanotechnology Conference and Trade Show - Nanotech 2003. 2003 Nanotechnology Conference and Trade Show - Nanotech 2003, vol. 2, pp. 558-561, 2003 Nanotechnology Conference and Trade Show - Nanotech 2003, San Francisco, CA, United States, 2/23/03.

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N2 - In biomanipulation research area, the reliable force measurement and modeling of biological molecules are essential techniques to estimate the material properties and a motion of the biological molecule. In this study, we introduce the system identification method to estimate motion of protein and material characteristics using AFM-based nanorobotic manipulation. Modeling of piezoresistive AFM cantilever and equivalent model for force-measurement system are presented. Based on equivalent, dynamic motion of a protein is efficiently estimated in real-time. In case of globular protein, damping coefficient and spring constant show good agreement between estimation results and actual values.

AB - In biomanipulation research area, the reliable force measurement and modeling of biological molecules are essential techniques to estimate the material properties and a motion of the biological molecule. In this study, we introduce the system identification method to estimate motion of protein and material characteristics using AFM-based nanorobotic manipulation. Modeling of piezoresistive AFM cantilever and equivalent model for force-measurement system are presented. Based on equivalent, dynamic motion of a protein is efficiently estimated in real-time. In case of globular protein, damping coefficient and spring constant show good agreement between estimation results and actual values.

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KW - System identification

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M3 - Conference contribution

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BT - 2003 Nanotechnology Conference and Trade Show - Nanotech 2003

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T2 - 2003 Nanotechnology Conference and Trade Show - Nanotech 2003

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System identification for motion of proteins using an AFM-based nanorobotic manipulation

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

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