Syphilis in injecting drug users: Clues for high-risk sexual behaviour in female IDUs

Roberto Muga, Josep Roca, Jordi Tor, Carme Pigem, Rosa Rodriguez, Jose Manuel Egea, David Vlahov, Alvaro Munoz

Research output: Contribution to journalArticle

Abstract

The objective was to measure the gender-specific differences for syphilis and for the sexual transmission of human immunodeficiency virus (HIV) in a cross-sectional analysis of injecting drug users (IDUs) admitted to detoxification between February 1987 and January 1990. HIV was determined by enzyme-linked immunosorbent assay (ELISA) and confirmed with Western blot. For syphilis reactive samples to a rapid plasma reagent (RFR) were confirmed with treponemal tests (FTA-ABS or MHA-TP). Of the 386 heterosexual IDUs, 68% were HIV-positive and 4.7% had serologic syphilis (RFR and FTA-ABS or MHA-TP positive). Syphilis was higher in women (12%) than in men (3%), and women reported a significantly (P <0.001) higher number of sex partners. Men had an IDU as a sex partner more often than women did (P = 0.001). Serologic syphilis in women was associated with having had more than one sexual partner in the previous year (P = 0.028) but this association was not present in men. HIV infection was not associated with syphilis in male IDUs. However, HIV was present in all women with syphilis that reported more than one partner.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalInternational Journal of STD and AIDS
Volume8
Issue number4
DOIs
StatePublished - 1997

Fingerprint

Syphilis
Risk-Taking
Drug Users
Sexual Behavior
HIV
Fluorescent Treponemal Antibody-Absorption Test
Sexual Partners
Heterosexuality
Virus Diseases
Cross-Sectional Studies
Western Blotting
Enzyme-Linked Immunosorbent Assay

Keywords

  • HIV
  • injecting drug use
  • sexual behaviour
  • syphilis

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Immunology

Cite this

Syphilis in injecting drug users : Clues for high-risk sexual behaviour in female IDUs. / Muga, Roberto; Roca, Josep; Tor, Jordi; Pigem, Carme; Rodriguez, Rosa; Egea, Jose Manuel; Vlahov, David; Munoz, Alvaro.

In: International Journal of STD and AIDS, Vol. 8, No. 4, 1997, p. 225-228.

Research output: Contribution to journalArticle

Muga, Roberto ; Roca, Josep ; Tor, Jordi ; Pigem, Carme ; Rodriguez, Rosa ; Egea, Jose Manuel ; Vlahov, David ; Munoz, Alvaro. / Syphilis in injecting drug users : Clues for high-risk sexual behaviour in female IDUs. In: International Journal of STD and AIDS. 1997 ; Vol. 8, No. 4. pp. 225-228.
@article{963b39449cd242bb97ab8664303d32b1,
title = "Syphilis in injecting drug users: Clues for high-risk sexual behaviour in female IDUs",
abstract = "The objective was to measure the gender-specific differences for syphilis and for the sexual transmission of human immunodeficiency virus (HIV) in a cross-sectional analysis of injecting drug users (IDUs) admitted to detoxification between February 1987 and January 1990. HIV was determined by enzyme-linked immunosorbent assay (ELISA) and confirmed with Western blot. For syphilis reactive samples to a rapid plasma reagent (RFR) were confirmed with treponemal tests (FTA-ABS or MHA-TP). Of the 386 heterosexual IDUs, 68{\%} were HIV-positive and 4.7{\%} had serologic syphilis (RFR and FTA-ABS or MHA-TP positive). Syphilis was higher in women (12{\%}) than in men (3{\%}), and women reported a significantly (P <0.001) higher number of sex partners. Men had an IDU as a sex partner more often than women did (P = 0.001). Serologic syphilis in women was associated with having had more than one sexual partner in the previous year (P = 0.028) but this association was not present in men. HIV infection was not associated with syphilis in male IDUs. However, HIV was present in all women with syphilis that reported more than one partner.",
keywords = "HIV, injecting drug use, sexual behaviour, syphilis",
author = "Roberto Muga and Josep Roca and Jordi Tor and Carme Pigem and Rosa Rodriguez and Egea, {Jose Manuel} and David Vlahov and Alvaro Munoz",
year = "1997",
doi = "10.1258/0956462971919967",
language = "English (US)",
volume = "8",
pages = "225--228",
journal = "International Journal of STD and AIDS",
issn = "0956-4624",
publisher = "SAGE Publications Ltd",
number = "4",

}

TY - JOUR

T1 - Syphilis in injecting drug users

T2 - Clues for high-risk sexual behaviour in female IDUs

AU - Muga, Roberto

AU - Roca, Josep

AU - Tor, Jordi

AU - Pigem, Carme

AU - Rodriguez, Rosa

AU - Egea, Jose Manuel

AU - Vlahov, David

AU - Munoz, Alvaro

PY - 1997

Y1 - 1997

N2 - The objective was to measure the gender-specific differences for syphilis and for the sexual transmission of human immunodeficiency virus (HIV) in a cross-sectional analysis of injecting drug users (IDUs) admitted to detoxification between February 1987 and January 1990. HIV was determined by enzyme-linked immunosorbent assay (ELISA) and confirmed with Western blot. For syphilis reactive samples to a rapid plasma reagent (RFR) were confirmed with treponemal tests (FTA-ABS or MHA-TP). Of the 386 heterosexual IDUs, 68% were HIV-positive and 4.7% had serologic syphilis (RFR and FTA-ABS or MHA-TP positive). Syphilis was higher in women (12%) than in men (3%), and women reported a significantly (P <0.001) higher number of sex partners. Men had an IDU as a sex partner more often than women did (P = 0.001). Serologic syphilis in women was associated with having had more than one sexual partner in the previous year (P = 0.028) but this association was not present in men. HIV infection was not associated with syphilis in male IDUs. However, HIV was present in all women with syphilis that reported more than one partner.

AB - The objective was to measure the gender-specific differences for syphilis and for the sexual transmission of human immunodeficiency virus (HIV) in a cross-sectional analysis of injecting drug users (IDUs) admitted to detoxification between February 1987 and January 1990. HIV was determined by enzyme-linked immunosorbent assay (ELISA) and confirmed with Western blot. For syphilis reactive samples to a rapid plasma reagent (RFR) were confirmed with treponemal tests (FTA-ABS or MHA-TP). Of the 386 heterosexual IDUs, 68% were HIV-positive and 4.7% had serologic syphilis (RFR and FTA-ABS or MHA-TP positive). Syphilis was higher in women (12%) than in men (3%), and women reported a significantly (P <0.001) higher number of sex partners. Men had an IDU as a sex partner more often than women did (P = 0.001). Serologic syphilis in women was associated with having had more than one sexual partner in the previous year (P = 0.028) but this association was not present in men. HIV infection was not associated with syphilis in male IDUs. However, HIV was present in all women with syphilis that reported more than one partner.

KW - HIV

KW - injecting drug use

KW - sexual behaviour

KW - syphilis

UR - http://www.scopus.com/inward/record.url?scp=0030945389&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030945389&partnerID=8YFLogxK

U2 - 10.1258/0956462971919967

DO - 10.1258/0956462971919967

M3 - Article

C2 - 9147154

AN - SCOPUS:0030945389

VL - 8

SP - 225

EP - 228

JO - International Journal of STD and AIDS

JF - International Journal of STD and AIDS

SN - 0956-4624

IS - 4

ER -