Synthesis of sulfated β-1,6-linked oligosaccharide mimetics: A novel potent inhibitor of HIV replication

Yoshitomo Suhara, Mie Ichikawa, James E K Hildreth, Yoshitaka Ichikawa

    Research output: Contribution to journalArticle

    Abstract

    A novel sulfated β(1→6)-linked oligosaccharide mimetics has been synthesized and found to be a potent inhibitor of HIV replication, with an IC50 of 1 μM.

    Original languageEnglish (US)
    Pages (from-to)2549-2552
    Number of pages4
    JournalTetrahedron Letters
    Volume37
    Issue number15
    DOIs
    StatePublished - Apr 8 1996

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    Oligosaccharides
    Inhibitory Concentration 50
    HIV

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    Synthesis of sulfated β-1,6-linked oligosaccharide mimetics : A novel potent inhibitor of HIV replication. / Suhara, Yoshitomo; Ichikawa, Mie; Hildreth, James E K; Ichikawa, Yoshitaka.

    In: Tetrahedron Letters, Vol. 37, No. 15, 08.04.1996, p. 2549-2552.

    Research output: Contribution to journalArticle

    Suhara, Yoshitomo ; Ichikawa, Mie ; Hildreth, James E K ; Ichikawa, Yoshitaka. / Synthesis of sulfated β-1,6-linked oligosaccharide mimetics : A novel potent inhibitor of HIV replication. In: Tetrahedron Letters. 1996 ; Vol. 37, No. 15. pp. 2549-2552.
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