Synthesis of partially non-peptidic neurotensin mimetics

Dharmpal S. Dood; Alan P. Kozikowski; Bernadette Cusack; Elliott Richelson

doi:10.1016/S0960-894X(01)80338-3

Synthesis of partially non-peptidic neurotensin mimetics

Dharmpal S. Dood, Alan P. Kozikowski, Bernadette Cusack, Elliott Richelson

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The synthesis of partially non-peptidic mimetics for NT(8-13) is described. The sequence Arg⁸Arg⁹Pro¹⁰ of NT(8-13) was replaced by an appropriately substituted indole-2-carboxylate as the non-peptidic equivalent.

Original language	English (US)
Pages (from-to)	1241-1246
Number of pages	6
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	4
Issue number	10
DOIs	https://doi.org/10.1016/S0960-894X(01)80338-3
State	Published - May 19 1994
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/S0960-894X(01)80338-3

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title = "Synthesis of partially non-peptidic neurotensin mimetics",

abstract = "The synthesis of partially non-peptidic mimetics for NT(8-13) is described. The sequence Arg8Arg9Pro10 of NT(8-13) was replaced by an appropriately substituted indole-2-carboxylate as the non-peptidic equivalent.",

author = "Dood, {Dharmpal S.} and Kozikowski, {Alan P.} and Bernadette Cusack and Elliott Richelson",

year = "1994",

month = may,

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doi = "10.1016/S0960-894X(01)80338-3",

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T1 - Synthesis of partially non-peptidic neurotensin mimetics

AU - Dood, Dharmpal S.

AU - Kozikowski, Alan P.

AU - Cusack, Bernadette

AU - Richelson, Elliott

PY - 1994/5/19

Y1 - 1994/5/19

N2 - The synthesis of partially non-peptidic mimetics for NT(8-13) is described. The sequence Arg8Arg9Pro10 of NT(8-13) was replaced by an appropriately substituted indole-2-carboxylate as the non-peptidic equivalent.

AB - The synthesis of partially non-peptidic mimetics for NT(8-13) is described. The sequence Arg8Arg9Pro10 of NT(8-13) was replaced by an appropriately substituted indole-2-carboxylate as the non-peptidic equivalent.

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U2 - 10.1016/S0960-894X(01)80338-3

DO - 10.1016/S0960-894X(01)80338-3

M3 - Article

AN - SCOPUS:0028225379

SN - 0960-894X

VL - 4

SP - 1241

EP - 1246

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 10

ER -

Synthesis of partially non-peptidic neurotensin mimetics

Abstract

ASJC Scopus subject areas

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