Because of the expected greater rate of coupling as compared to naphthylamine, 3-methoxy-1-naphthylamine and 4-methoxy-2-naphthylamine have been synthesized for use in the preparation of chromogenic substrates for the histochemical demonstration of amidases and peptidases. The chloroacetamides, trifluoroacetamides and L-leucyl-4-methoxy-2-naphthyl amide also were prepared. The last derivative is a superior reagent for the histochemical demonstration of leucine amino peptidase.
ASJC Scopus subject areas
- Colloid and Surface Chemistry