Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

Narayan C. Rath, Arnold L. Oronsky, S. S. Kerwar

Research output: Contribution to journalArticlepeer-review

Abstract

Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.

Original languageEnglish (US)
Pages (from-to)39-46
Number of pages8
JournalClinical Immunology and Immunopathology
Volume47
Issue number1
DOIs
StatePublished - Apr 1988

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology

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