Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.
ASJC Scopus subject areas
- Immunology and Allergy
- Pathology and Forensic Medicine