Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

Narayan C. Rath, Arnold L. Oronsky, S. S. Kerwar

Research output: Contribution to journalArticle

Abstract

Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.

Original languageEnglish (US)
Pages (from-to)39-46
Number of pages8
JournalClinical Immunology and Immunopathology
Volume47
Issue number1
DOIs
StatePublished - 1988
Externally publishedYes

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Chondrocytes
Interleukin-1
Articular Cartilage
Macrophages

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pathology and Forensic Medicine

Cite this

Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture. / Rath, Narayan C.; Oronsky, Arnold L.; Kerwar, S. S.

In: Clinical Immunology and Immunopathology, Vol. 47, No. 1, 1988, p. 39-46.

Research output: Contribution to journalArticle

Rath, Narayan C. ; Oronsky, Arnold L. ; Kerwar, S. S. / Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture. In: Clinical Immunology and Immunopathology. 1988 ; Vol. 47, No. 1. pp. 39-46.
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