Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

Narayan C. Rath; Arnold L. Oronsky; S. S. Kerwar

doi:10.1016/0090-1229(88)90143-2

Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

Narayan C. Rath, Arnold L. Oronsky, S. S. Kerwar

School of Medicine

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31 Scopus citations

Abstract

Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.

Original language	English (US)
Pages (from-to)	39-46
Number of pages	8
Journal	Clinical Immunology and Immunopathology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1016/0090-1229(88)90143-2
State	Published - Apr 1988

ASJC Scopus subject areas

Immunology and Allergy
Pathology and Forensic Medicine
Immunology

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title = "Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture",

abstract = "Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.",

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N2 - Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.

AB - Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1α. Isolated chondrocytes and those grown in culture can express Ia.

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Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture

Abstract

ASJC Scopus subject areas

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