Synthesis of fluorine-containing isosteres of sphingosine as inactivators of protein kinase C

Alan P. Kozikowski, Jiang Ping Wu

Research output: Contribution to journalArticle

Abstract

Syntheses of isosteres of D-sphingosine in which either the primary or the secondary hydroxyl group of the parent compound has been replaced by a fluorine substituent are described.

Original languageEnglish (US)
Pages (from-to)4309-4312
Number of pages4
JournalTetrahedron Letters
Volume31
Issue number30
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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