Synthesis of Chromogenic Substrates for the Assay of Aminopeptidase Activity

Theodore P. Goldstein, Robert E. Plapinger, Marvin M. Nachlas, Arnold M. Seligman

Research output: Contribution to journalArticlepeer-review

Abstract

The 2-naphthylamides of six amino acids were prepared as substrates in order to determine if the enzymatic splitting of the amide link is due to a non-specific aminopeptidase or an aminopeptidase specific for each amino acid.

Original languageEnglish (US)
Pages (from-to)852-857
Number of pages6
JournalJournal of Medicinal and Pharmaceutical Chemistry
Volume5
Issue number4
DOIs
StatePublished - Jul 1 1962

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery
  • Organic Chemistry

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