Synthesis of cerebrosides by intact oligodendroglia maintained in culture

S. E. Poduslo; G. M. McKhann

doi:10.1016/0304-3940(77)90040-4

Synthesis of cerebrosides by intact oligodendroglia maintained in culture

S. E. Poduslo, G. M. McKhann

School of Arts and Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Oligodendroglia, isolated in bulk from dissected white matter from lamb brain, can now be maintained in culture. The cells actively synthesize both cerebrosides and sulfatides, lipids found concentrated in myelin, as well as other myelin components. Thus this provides a useful model to study myelin assembly in vitro.

Original language	English (US)
Pages (from-to)	159-163
Number of pages	5
Journal	Neuroscience Letters
Volume	5
Issue number	3-4
DOIs	https://doi.org/10.1016/0304-3940(77)90040-4
State	Published - Jul 1977

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(77)90040-4

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title = "Synthesis of cerebrosides by intact oligodendroglia maintained in culture",

abstract = "Oligodendroglia, isolated in bulk from dissected white matter from lamb brain, can now be maintained in culture. The cells actively synthesize both cerebrosides and sulfatides, lipids found concentrated in myelin, as well as other myelin components. Thus this provides a useful model to study myelin assembly in vitro.",

author = "Poduslo, {S. E.} and McKhann, {G. M.}",

note = "Funding Information: The technical assistance of K. Miller and R~ Piasecki is gratefully acknowledged. This work was supported by funds from the John A. Hartford Foundation; U.S.P.HoS. Grants NS 10920, 08719, and 02491; and the Multiple Sclerosis Society.",

year = "1977",

month = jul,

doi = "10.1016/0304-3940(77)90040-4",

language = "English (US)",

volume = "5",

pages = "159--163",

journal = "Neuroscience Letters",

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publisher = "Elsevier Ireland Ltd",

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AU - Poduslo, S. E.

AU - McKhann, G. M.

N1 - Funding Information: The technical assistance of K. Miller and R~ Piasecki is gratefully acknowledged. This work was supported by funds from the John A. Hartford Foundation; U.S.P.HoS. Grants NS 10920, 08719, and 02491; and the Multiple Sclerosis Society.

PY - 1977/7

Y1 - 1977/7

N2 - Oligodendroglia, isolated in bulk from dissected white matter from lamb brain, can now be maintained in culture. The cells actively synthesize both cerebrosides and sulfatides, lipids found concentrated in myelin, as well as other myelin components. Thus this provides a useful model to study myelin assembly in vitro.

AB - Oligodendroglia, isolated in bulk from dissected white matter from lamb brain, can now be maintained in culture. The cells actively synthesize both cerebrosides and sulfatides, lipids found concentrated in myelin, as well as other myelin components. Thus this provides a useful model to study myelin assembly in vitro.

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JF - Neuroscience Letters

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Synthesis of cerebrosides by intact oligodendroglia maintained in culture

Abstract

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