Synthesis and study of a methoxyhydroperoxide-androstenedione derivative; analogue of a potential aromatase intermediate

Philip A. Cole, Cecil H. Robinson

Research output: Contribution to journalArticlepeer-review

Abstract

A methoxyhydroperoxide analogue (12) to a proposed aromatase intermediate has been synthesized by ozonolysis of methoxyvinyl compound (7) in the presence of methanol; it has been shown not to produce estrone with or without acetylation, but the free hydroperoxide apparently undergoes a facile, stereospecific intramolecular epoxidation.

Original languageEnglish (US)
Pages (from-to)1651-1653
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number22
DOIs
StatePublished - Jan 1 1986

ASJC Scopus subject areas

  • Molecular Medicine

Fingerprint Dive into the research topics of 'Synthesis and study of a methoxyhydroperoxide-androstenedione derivative; analogue of a potential aromatase intermediate'. Together they form a unique fingerprint.

Cite this