A methoxyhydroperoxide analogue (12) to a proposed aromatase intermediate has been synthesized by ozonolysis of methoxyvinyl compound (7) in the presence of methanol; it has been shown not to produce estrone with or without acetylation, but the free hydroperoxide apparently undergoes a facile, stereospecific intramolecular epoxidation.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of the Chemical Society, Chemical Communications|
|State||Published - Jan 1 1986|
ASJC Scopus subject areas
- Molecular Medicine