Syntheses and Interactions of Oligodeoxyribonucleotides Containing 2'-Amino-2'-Deoxyuridine

Paul S. Miller, Purshotam Bhan, Lou Sing Kan

Research output: Contribution to journalArticle

Abstract

Oligodeoxyribonurc1eotides containing '-amino-2'-deoxy uridine (dU) were synthesized and their ability to form duplexes with complementary DNA or RNA oligonucleotides was studied. Substitution of dU with dU in these oligomers results in lowered Tms of the duplexes.

Original languageEnglish (US)
Pages (from-to)785-792
Number of pages8
JournalNucleosides and Nucleotides
Volume12
Issue number8
DOIs
StatePublished - Sep 1 1993

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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