TY - JOUR
T1 - Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature
AU - DiMeco, F.
AU - Clatterbuck, R. E.
AU - Li, K. W.
AU - McCarthy, E. F.
AU - Olivi, A.
PY - 2000
Y1 - 2000
N2 - The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.
AB - The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.
KW - Skull
KW - Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome
UR - http://www.scopus.com/inward/record.url?scp=0034433826&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034433826&partnerID=8YFLogxK
U2 - 10.3171/jns.2000.93.4.0693
DO - 10.3171/jns.2000.93.4.0693
M3 - Article
C2 - 11014551
AN - SCOPUS:0034433826
SN - 0022-3085
VL - 93
SP - 693
EP - 697
JO - Journal of neurosurgery
JF - Journal of neurosurgery
IS - 4
ER -