Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature

F. DiMeco, R. E. Clatterbuck, K. W. Li, Edward F McCarthy, Alessandro Olivi

Research output: Contribution to journalArticle

Abstract

The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.

Original languageEnglish (US)
Pages (from-to)693-697
Number of pages5
JournalJournal of Neurosurgery
Volume93
Issue number4
StatePublished - 2000

Fingerprint

Hyperostosis
Osteitis
Synovitis
Acne Vulgaris
Skull
Bone and Bones
Names
Differential Diagnosis
Skin

Keywords

  • Skull
  • Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature. / DiMeco, F.; Clatterbuck, R. E.; Li, K. W.; McCarthy, Edward F; Olivi, Alessandro.

In: Journal of Neurosurgery, Vol. 93, No. 4, 2000, p. 693-697.

Research output: Contribution to journalArticle

@article{a9b8313f0f804315b43eb4181e46200e,
title = "Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature",
abstract = "The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.",
keywords = "Skull, Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome",
author = "F. DiMeco and Clatterbuck, {R. E.} and Li, {K. W.} and McCarthy, {Edward F} and Alessandro Olivi",
year = "2000",
language = "English (US)",
volume = "93",
pages = "693--697",
journal = "Journal of Neurosurgery",
issn = "0022-3085",
publisher = "American Association of Neurological Surgeons",
number = "4",

}

TY - JOUR

T1 - Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature

AU - DiMeco, F.

AU - Clatterbuck, R. E.

AU - Li, K. W.

AU - McCarthy, Edward F

AU - Olivi, Alessandro

PY - 2000

Y1 - 2000

N2 - The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.

AB - The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.

KW - Skull

KW - Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome

UR - http://www.scopus.com/inward/record.url?scp=0034433826&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034433826&partnerID=8YFLogxK

M3 - Article

VL - 93

SP - 693

EP - 697

JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

SN - 0022-3085

IS - 4

ER -