Synovial cell sarcoma of the vulva: Multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy

Caroline L. Holloway, Anthony H. Russell, Michael Muto, Michele Albert, Akila N. Viswanathan

Research output: Contribution to journalArticle

Abstract

Background: Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. Case: We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimodality management, including preoperative intensity-modulated radiation therapy, radical hemivulvectomy, flap reconstruction, interstitial low-dose-rate brachytherapy boost, and adjuvant chemotherapy. Conclusion: Based on this case and the limited data in the literature, multimodality treatment of advanced soft tissue sarcoma of the vulva may optimize local control and minimize toxicity while preserving sexual function.

Original languageEnglish (US)
Pages (from-to)253-256
Number of pages4
JournalGynecologic oncology
Volume104
Issue number1
DOIs
StatePublished - Jan 1 2007

Keywords

  • Brachytherapy
  • Radiation therapy
  • Vulvar sarcoma

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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