TY - JOUR
T1 - Synovial cell sarcoma of the vulva
T2 - Multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy
AU - Holloway, Caroline L.
AU - Russell, Anthony H.
AU - Muto, Michael
AU - Albert, Michele
AU - Viswanathan, Akila N.
PY - 2007/1
Y1 - 2007/1
N2 - Background: Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. Case: We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimodality management, including preoperative intensity-modulated radiation therapy, radical hemivulvectomy, flap reconstruction, interstitial low-dose-rate brachytherapy boost, and adjuvant chemotherapy. Conclusion: Based on this case and the limited data in the literature, multimodality treatment of advanced soft tissue sarcoma of the vulva may optimize local control and minimize toxicity while preserving sexual function.
AB - Background: Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. Case: We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimodality management, including preoperative intensity-modulated radiation therapy, radical hemivulvectomy, flap reconstruction, interstitial low-dose-rate brachytherapy boost, and adjuvant chemotherapy. Conclusion: Based on this case and the limited data in the literature, multimodality treatment of advanced soft tissue sarcoma of the vulva may optimize local control and minimize toxicity while preserving sexual function.
KW - Brachytherapy
KW - Radiation therapy
KW - Vulvar sarcoma
UR - http://www.scopus.com/inward/record.url?scp=33845965375&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845965375&partnerID=8YFLogxK
U2 - 10.1016/j.ygyno.2006.09.018
DO - 10.1016/j.ygyno.2006.09.018
M3 - Article
C2 - 17070900
AN - SCOPUS:33845965375
SN - 0090-8258
VL - 104
SP - 253
EP - 256
JO - Gynecologic oncology
JF - Gynecologic oncology
IS - 1
ER -