Synaptic morphology and the influence of auditory experience

Jahn N. O'Neil, Catherine J. Connelly, Charles J. Limb, David K. Ryugo

Research output: Contribution to journalReview articlepeer-review

Abstract

The auditory experience is crucial for the normal development and maturation of brain structure and the maintenance of the auditory pathways. The specific aims of this review are (i) to provide a brief background of the synaptic morphology of the endbulb of Held in hearing and deaf animals; (ii) to argue the importance of this large synaptic ending in linking neural activity along ascending pathways to environmental acoustic events; (iii) to describe how the re-introduction of electrical activity changes this synapse; and (iv) to examine how changes at the endbulb synapse initiate trans-synaptic changes in ascending auditory projections to the superior olivary complex, the inferior complex, and the auditory cortex.

Original languageEnglish (US)
Pages (from-to)118-130
Number of pages13
JournalHearing Research
Volume279
Issue number1-2
DOIs
StatePublished - Sep 2011

ASJC Scopus subject areas

  • Sensory Systems

Fingerprint Dive into the research topics of 'Synaptic morphology and the influence of auditory experience'. Together they form a unique fingerprint.

Cite this