Abstract
The central tegmental tract (CTT) is mainly the extrapyramidal tract connecting between the red nucleus and the inferior olivary nucleus. There are only a few case reports describing CTT abnormalities on magnetic resonance imaging (MRI) in children. Our purpose was to evaluate the frequency of CTT lesions and their characteristics on MRI, and to correlate the MR imaging findings with clinical features. We reviewed retrospectively the MR images of 392 children (215 boys and 177 girls) ranging in age from 1 to 6 years. To evaluate symmetrical CTT hyperintense lesions, we defined a CTT lesion as an area of bilateral symmetrical hyperintensity in the tegmentum pontis on both T2-weighted images and diffusion-weighted images in more than two slices. We measured the ADC (apparent diffusion coefficient) values of symmetrical CTT hyperintensity, and compared them with those of children without CTT abnormality. CTT lesions were detected in 20 (5.1%) of the 392 children. The mean ADC value for these 20 children was significantly lower than that of the normal CTT (p
| Original language | English (US) |
|---|---|
| Pages (from-to) | 462-469 |
| Number of pages | 8 |
| Journal | European Radiology |
| Volume | 19 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2009 |
| Externally published | Yes |
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Keywords
- Central tegmental tract
- Cerebral palsy
- Congenital metabolic disorder
- CTT
- Magnetic resonance imaging
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Symmetrical central tegmental tract (CTT) hyperintense lesions on magnetic resonance imaging in children. / Yoshida, Shoko; Hayakawa, Katsumi; Yamamoto, Akira; Aida, Noriko; Okano, Souzo; Matsushita, Hiroko; Kanda, Toyoko; Yamori, Yuriko; Yoshida, Naoko; Hirota, Haruyo.
In: European Radiology, Vol. 19, No. 2, 2009, p. 462-469.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Symmetrical central tegmental tract (CTT) hyperintense lesions on magnetic resonance imaging in children
AU - Yoshida, Shoko
AU - Hayakawa, Katsumi
AU - Yamamoto, Akira
AU - Aida, Noriko
AU - Okano, Souzo
AU - Matsushita, Hiroko
AU - Kanda, Toyoko
AU - Yamori, Yuriko
AU - Yoshida, Naoko
AU - Hirota, Haruyo
PY - 2009
Y1 - 2009
N2 - The central tegmental tract (CTT) is mainly the extrapyramidal tract connecting between the red nucleus and the inferior olivary nucleus. There are only a few case reports describing CTT abnormalities on magnetic resonance imaging (MRI) in children. Our purpose was to evaluate the frequency of CTT lesions and their characteristics on MRI, and to correlate the MR imaging findings with clinical features. We reviewed retrospectively the MR images of 392 children (215 boys and 177 girls) ranging in age from 1 to 6 years. To evaluate symmetrical CTT hyperintense lesions, we defined a CTT lesion as an area of bilateral symmetrical hyperintensity in the tegmentum pontis on both T2-weighted images and diffusion-weighted images in more than two slices. We measured the ADC (apparent diffusion coefficient) values of symmetrical CTT hyperintensity, and compared them with those of children without CTT abnormality. CTT lesions were detected in 20 (5.1%) of the 392 children. The mean ADC value for these 20 children was significantly lower than that of the normal CTT (p
AB - The central tegmental tract (CTT) is mainly the extrapyramidal tract connecting between the red nucleus and the inferior olivary nucleus. There are only a few case reports describing CTT abnormalities on magnetic resonance imaging (MRI) in children. Our purpose was to evaluate the frequency of CTT lesions and their characteristics on MRI, and to correlate the MR imaging findings with clinical features. We reviewed retrospectively the MR images of 392 children (215 boys and 177 girls) ranging in age from 1 to 6 years. To evaluate symmetrical CTT hyperintense lesions, we defined a CTT lesion as an area of bilateral symmetrical hyperintensity in the tegmentum pontis on both T2-weighted images and diffusion-weighted images in more than two slices. We measured the ADC (apparent diffusion coefficient) values of symmetrical CTT hyperintensity, and compared them with those of children without CTT abnormality. CTT lesions were detected in 20 (5.1%) of the 392 children. The mean ADC value for these 20 children was significantly lower than that of the normal CTT (p
KW - Central tegmental tract
KW - Cerebral palsy
KW - Congenital metabolic disorder
KW - CTT
KW - Magnetic resonance imaging
UR - http://www.scopus.com/inward/record.url?scp=59249100459&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=59249100459&partnerID=8YFLogxK
U2 - 10.1007/s00330-008-1167-7
DO - 10.1007/s00330-008-1167-7
M3 - Article
C2 - 18795297
AN - SCOPUS:59249100459
VL - 19
SP - 462
EP - 469
JO - European Radiology
JF - European Radiology
SN - 0938-7994
IS - 2
ER -