Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs

Shaina D. Holman, Regina Campbell-Malone, Peng Ding, Estela M. Gierbolini-Norat, Stacey L. Lukasik, Danielle R. Waranch, Rebecca Z. German

Research output: Contribution to journalArticle

Abstract

Objectives/Hypothesis Abnormal kinematics during swallowing can result in aspiration, which may become life threatening. We tested the role of palatal sensation in the motor control of pharyngeal swallow in infants. Study Design In eight infant pigs, we reduced palatal sensation using local anesthesia (PLA) and measured the impact on swallowing kinematics and airway protection. Methods The pigs drank milk containing barium while we simultaneously recorded videofluoroscopy and electromyography from fine wire bipolar electrodes in several hyolaryngeal muscles. We compared these results to control feedings and feedings following palatal saline injections. Results After PLA, four pigs had extreme jaw movements and abnormal tongue movement uncharacteristic of sucking. For this reason, we evaluated differences between these group B pigs and the others that could suck normally after PLA (group A). In the four group A pigs, after PLA there was less hyoid elevation (P

Original languageEnglish (US)
Pages (from-to)436-445
Number of pages10
JournalLaryngoscope
Volume124
Issue number2
DOIs
StatePublished - Feb 2014

Fingerprint

Local Anesthesia
Deglutition
Biomechanical Phenomena
Swine
Hypesthesia
Dyskinesias
Electromyography
Barium
Jaw
Tongue
Electrodes
Milk
Muscles
Injections

Keywords

  • animal model
  • Dysphagia
  • electromyography
  • greater palatine nerve
  • infant
  • nasopalatine nerve
  • neurophysiology
  • pig
  • videofluoroscopy

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

Cite this

Holman, S. D., Campbell-Malone, R., Ding, P., Gierbolini-Norat, E. M., Lukasik, S. L., Waranch, D. R., & German, R. Z. (2014). Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs. Laryngoscope, 124(2), 436-445. https://doi.org/10.1002/lary.24204

Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs. / Holman, Shaina D.; Campbell-Malone, Regina; Ding, Peng; Gierbolini-Norat, Estela M.; Lukasik, Stacey L.; Waranch, Danielle R.; German, Rebecca Z.

In: Laryngoscope, Vol. 124, No. 2, 02.2014, p. 436-445.

Research output: Contribution to journalArticle

Holman, SD, Campbell-Malone, R, Ding, P, Gierbolini-Norat, EM, Lukasik, SL, Waranch, DR & German, RZ 2014, 'Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs', Laryngoscope, vol. 124, no. 2, pp. 436-445. https://doi.org/10.1002/lary.24204
Holman SD, Campbell-Malone R, Ding P, Gierbolini-Norat EM, Lukasik SL, Waranch DR et al. Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs. Laryngoscope. 2014 Feb;124(2):436-445. https://doi.org/10.1002/lary.24204
Holman, Shaina D. ; Campbell-Malone, Regina ; Ding, Peng ; Gierbolini-Norat, Estela M. ; Lukasik, Stacey L. ; Waranch, Danielle R. ; German, Rebecca Z. / Swallowing kinematics and airway protection after palatal local anesthesia in infant pigs. In: Laryngoscope. 2014 ; Vol. 124, No. 2. pp. 436-445.
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