Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology

William M. Curtin, Karmaine A. Millington, Tochi Ibekwe, Serdar H. Ural

Research output: Contribution to journalArticle

Abstract

Objective. Our objective was determining if abnormal Doppler evaluation had a higher prevalence of placental pathology compared to normal Doppler in suspected fetal growth restriction (FGR) of cases delivered at 37 weeks. Study Design. This retrospective cohort study of suspected FGR singletons with antenatal Doppler evaluation delivered at 37 weeks had a primary outcome of the prevalence of placental pathology related to FGR. Significance was defined as p≤0.05. Results. Of 100 pregnancies 46 and 54 were in the abnormal and normal Doppler cohorts, respectively. Placental pathology was more prevalent with any abnormal Doppler, 84.8% versus 55.6%, odds ratio (OR) 4.46, 95% confidence interval (CI): 1.55, 13.22, and p=0.002. Abnormal middle cerebral artery (MCA) Doppler had a higher prevalence: 96.2% versus 54.8%, OR 20.7, 95% CI: 2.54, 447.1, and p<0.001. Conclusion. Abnormal Doppler was associated with more placental pathology in comparison to normal Doppler in fetuses with suspected FGR. Abnormal MCA Doppler had the strongest association.

Original languageEnglish (US)
Article number3723879
JournalBioMed Research International
Volume2017
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

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Pathology
Fetal Development
Middle Cerebral Artery
Odds Ratio
Confidence Intervals
Fetus
Cohort Studies
Retrospective Studies
Pregnancy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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Suspected Fetal Growth Restriction at 37 Weeks : A Comparison of Doppler and Placental Pathology. / Curtin, William M.; Millington, Karmaine A.; Ibekwe, Tochi; Ural, Serdar H.

In: BioMed Research International, Vol. 2017, 3723879, 01.01.2017.

Research output: Contribution to journalArticle

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