Abstract
Melanized Cryptococcus neoformans cells were less susceptible than nonmelanized cells to the fungicidal effects of nitrogen- and oxygen-derived oxidants. The results support the hypothesis that the phenoloxidase enzyme system contributes to virulence by protecting C. neoformans against nitrogen- and oxygen-derived oxidative antimicrobial molecules produced by immune effector cells.
Original language | English (US) |
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Pages (from-to) | 3004-3007 |
Number of pages | 4 |
Journal | Infection and immunity |
Volume | 62 |
Issue number | 7 |
State | Published - 1994 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases