Susceptibilities of serial Cryptococcus neoformans isolates from patients with recurrent cryptococcal meningitis to amphotericin B and fluconazole

A. Casadevall, E. D. Spitzer, D. Webb, M. G. Rinaldi

Research output: Contribution to journalComment/debatepeer-review

Abstract

Amphotericin B and fluconazole susceptibilities of 13 Cryptococcus neoformans isolates from five patients with recurrent cryptococcal meningitis were determined. For each patient, serial isolates showed no increase in antibiotic resistance relative to the initial isolate. For these patients, recurrent disease was not due to drug resistance but may reflect changes in immune function and/or poor compliance.

Original languageEnglish (US)
Pages (from-to)1383-1386
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume37
Issue number6
DOIs
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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