Survival and right ventricular performance for matched children after stage-1 Norwood: Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015.

Travis J. Wilder, Brian W. McCrindle, Alistair B. Phillips, Eugene H. Blackstone, Jeevanantham Rajeswaran, William G. Williams, William M. Decampli, Jeffrey P. Jacobs, Marshall L Jacobs, Tara Karamlou, Paul M. Kirshbom, Gary K. Lofland, Gerhard Ziemer, Edward J. Hickey

Research output: Contribution to journalArticle

Abstract

Objective Early survival advantages after Norwood with right-ventricle-(RV)-to-pulmonary-artery conduit (NW-RVPA) over Norwood-operation with a Blalock-Taussig shunt (NW-BT) are offset by concerns regarding delayed RV dysfunction. We compared trends in survival, RV dysfunction, and tricuspid valve regurgitation (TR) between NW-RVPA and NW-BT for propensity-matched neonates with critical left ventricular outflow tract obstruction (LVOTO). Methods In an inception cohort (2005-2014; 21 institutions), 454 neonates with critical LVOTO underwent Norwood stage 1. Propensity-score matching paired 169 NW-RVPA patients with 169 NW-BT patients. End-states were compared between NW-RVPA and NW-BT using competing-risks, multiphase, parametric, hazard analysis. Post-Norwood echocardiogram reports (n = 2993) were used to grade RV dysfunction and TR. Time-related prevalence of

Original languageEnglish (US)
Pages (from-to)1440-1452.e8
JournalJournal of Thoracic and Cardiovascular Surgery
Volume150
Issue number6
DOIs
StatePublished - Dec 1 2015

Fingerprint

Blalock-Taussig Procedure
Ventricular Outflow Obstruction
Tricuspid Valve Insufficiency
Pulmonary Artery
Heart Ventricles
Norwood Procedures
Newborn Infant
Propensity Score
Survival

Keywords

  • congenital heart disease
  • critical left ventricular outflow tract obstruction
  • hypoplastic left heart syndrome
  • Norwood operation
  • single ventricle

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Survival and right ventricular performance for matched children after stage-1 Norwood : Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015. / Wilder, Travis J.; McCrindle, Brian W.; Phillips, Alistair B.; Blackstone, Eugene H.; Rajeswaran, Jeevanantham; Williams, William G.; Decampli, William M.; Jacobs, Jeffrey P.; Jacobs, Marshall L; Karamlou, Tara; Kirshbom, Paul M.; Lofland, Gary K.; Ziemer, Gerhard; Hickey, Edward J.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 150, No. 6, 01.12.2015, p. 1440-1452.e8.

Research output: Contribution to journalArticle

Wilder, Travis J. ; McCrindle, Brian W. ; Phillips, Alistair B. ; Blackstone, Eugene H. ; Rajeswaran, Jeevanantham ; Williams, William G. ; Decampli, William M. ; Jacobs, Jeffrey P. ; Jacobs, Marshall L ; Karamlou, Tara ; Kirshbom, Paul M. ; Lofland, Gary K. ; Ziemer, Gerhard ; Hickey, Edward J. / Survival and right ventricular performance for matched children after stage-1 Norwood : Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015. In: Journal of Thoracic and Cardiovascular Surgery. 2015 ; Vol. 150, No. 6. pp. 1440-1452.e8.
@article{e2a15a562df9491baf89067399e209d1,
title = "Survival and right ventricular performance for matched children after stage-1 Norwood: Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015.",
abstract = "Objective Early survival advantages after Norwood with right-ventricle-(RV)-to-pulmonary-artery conduit (NW-RVPA) over Norwood-operation with a Blalock-Taussig shunt (NW-BT) are offset by concerns regarding delayed RV dysfunction. We compared trends in survival, RV dysfunction, and tricuspid valve regurgitation (TR) between NW-RVPA and NW-BT for propensity-matched neonates with critical left ventricular outflow tract obstruction (LVOTO). Methods In an inception cohort (2005-2014; 21 institutions), 454 neonates with critical LVOTO underwent Norwood stage 1. Propensity-score matching paired 169 NW-RVPA patients with 169 NW-BT patients. End-states were compared between NW-RVPA and NW-BT using competing-risks, multiphase, parametric, hazard analysis. Post-Norwood echocardiogram reports (n = 2993) were used to grade RV dysfunction and TR. Time-related prevalence of",
keywords = "congenital heart disease, critical left ventricular outflow tract obstruction, hypoplastic left heart syndrome, Norwood operation, single ventricle",
author = "Wilder, {Travis J.} and McCrindle, {Brian W.} and Phillips, {Alistair B.} and Blackstone, {Eugene H.} and Jeevanantham Rajeswaran and Williams, {William G.} and Decampli, {William M.} and Jacobs, {Jeffrey P.} and Jacobs, {Marshall L} and Tara Karamlou and Kirshbom, {Paul M.} and Lofland, {Gary K.} and Gerhard Ziemer and Hickey, {Edward J.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1016/j.jtcvs.2015.06.069",
language = "English (US)",
volume = "150",
pages = "1440--1452.e8",
journal = "Journal of Thoracic and Cardiovascular Surgery",
issn = "0022-5223",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Survival and right ventricular performance for matched children after stage-1 Norwood

T2 - Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015.

AU - Wilder, Travis J.

AU - McCrindle, Brian W.

AU - Phillips, Alistair B.

AU - Blackstone, Eugene H.

AU - Rajeswaran, Jeevanantham

AU - Williams, William G.

AU - Decampli, William M.

AU - Jacobs, Jeffrey P.

AU - Jacobs, Marshall L

AU - Karamlou, Tara

AU - Kirshbom, Paul M.

AU - Lofland, Gary K.

AU - Ziemer, Gerhard

AU - Hickey, Edward J.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Objective Early survival advantages after Norwood with right-ventricle-(RV)-to-pulmonary-artery conduit (NW-RVPA) over Norwood-operation with a Blalock-Taussig shunt (NW-BT) are offset by concerns regarding delayed RV dysfunction. We compared trends in survival, RV dysfunction, and tricuspid valve regurgitation (TR) between NW-RVPA and NW-BT for propensity-matched neonates with critical left ventricular outflow tract obstruction (LVOTO). Methods In an inception cohort (2005-2014; 21 institutions), 454 neonates with critical LVOTO underwent Norwood stage 1. Propensity-score matching paired 169 NW-RVPA patients with 169 NW-BT patients. End-states were compared between NW-RVPA and NW-BT using competing-risks, multiphase, parametric, hazard analysis. Post-Norwood echocardiogram reports (n = 2993) were used to grade RV dysfunction and TR. Time-related prevalence of

AB - Objective Early survival advantages after Norwood with right-ventricle-(RV)-to-pulmonary-artery conduit (NW-RVPA) over Norwood-operation with a Blalock-Taussig shunt (NW-BT) are offset by concerns regarding delayed RV dysfunction. We compared trends in survival, RV dysfunction, and tricuspid valve regurgitation (TR) between NW-RVPA and NW-BT for propensity-matched neonates with critical left ventricular outflow tract obstruction (LVOTO). Methods In an inception cohort (2005-2014; 21 institutions), 454 neonates with critical LVOTO underwent Norwood stage 1. Propensity-score matching paired 169 NW-RVPA patients with 169 NW-BT patients. End-states were compared between NW-RVPA and NW-BT using competing-risks, multiphase, parametric, hazard analysis. Post-Norwood echocardiogram reports (n = 2993) were used to grade RV dysfunction and TR. Time-related prevalence of

KW - congenital heart disease

KW - critical left ventricular outflow tract obstruction

KW - hypoplastic left heart syndrome

KW - Norwood operation

KW - single ventricle

UR - http://www.scopus.com/inward/record.url?scp=84948116659&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948116659&partnerID=8YFLogxK

U2 - 10.1016/j.jtcvs.2015.06.069

DO - 10.1016/j.jtcvs.2015.06.069

M3 - Article

C2 - 26254760

AN - SCOPUS:84948116659

VL - 150

SP - 1440-1452.e8

JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

SN - 0022-5223

IS - 6

ER -