TY - JOUR
T1 - Survey of the phenotypes of susceptibility to β-lactams in enterobacteriaceae at the pitie-salpetriere hospital
AU - Jarlier, V.
AU - Bismuth, R.
AU - Nicolas, M. H.
AU - Nguyen, J.
AU - Truffot, C.
AU - Grosset, J.
PY - 1984
Y1 - 1984
N2 - The phenotypes of susceptibility to ampicillin, carbenicillin, cephalothin, cefamandole, cefoxitin and cefotaxime were determined by the disc-diffusion method in 10,994 Enterobacteriaceae consecutively isolated from in-patients during 18 months. The susceptible phenotypes were much more frequent among Escherichia coli, Proteus mirabilis and Klebsiella (67.4 to 84.8%) than among Serratia, Enterobacter and Citrobacter (8.8 to 35.5%). In all species the most common resistance phenotypes were to ampicillin and carbenicillin: E. coli (28%), Pr. mirabilis (15.2%), Klebsiella (23.8%), indole-positive Proteus (33.3%), Serratia (74.4%), Enterobacter (61.4%) and Citrobacter (74.8%). Among E. coli, 4.6% of the strains were resistant to ampicillin and cephalothin but susceptible to carbenicillin. Among E. coli Pr. mirabilis and Klebsiella the strains susceptible only to cefotaxime represented 0.3 to 5% and no cefotaxime-resistant strain was isolated; whereas among Serratia, Enterobacter and Citrobacter the former represented 28.3 to 58.3% and the latter 7.5 to 18.5%. Some important differences in the distribution of the phenotypes according to the type of ward were observed.
AB - The phenotypes of susceptibility to ampicillin, carbenicillin, cephalothin, cefamandole, cefoxitin and cefotaxime were determined by the disc-diffusion method in 10,994 Enterobacteriaceae consecutively isolated from in-patients during 18 months. The susceptible phenotypes were much more frequent among Escherichia coli, Proteus mirabilis and Klebsiella (67.4 to 84.8%) than among Serratia, Enterobacter and Citrobacter (8.8 to 35.5%). In all species the most common resistance phenotypes were to ampicillin and carbenicillin: E. coli (28%), Pr. mirabilis (15.2%), Klebsiella (23.8%), indole-positive Proteus (33.3%), Serratia (74.4%), Enterobacter (61.4%) and Citrobacter (74.8%). Among E. coli, 4.6% of the strains were resistant to ampicillin and cephalothin but susceptible to carbenicillin. Among E. coli Pr. mirabilis and Klebsiella the strains susceptible only to cefotaxime represented 0.3 to 5% and no cefotaxime-resistant strain was isolated; whereas among Serratia, Enterobacter and Citrobacter the former represented 28.3 to 58.3% and the latter 7.5 to 18.5%. Some important differences in the distribution of the phenotypes according to the type of ward were observed.
UR - http://www.scopus.com/inward/record.url?scp=0021605390&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021605390&partnerID=8YFLogxK
U2 - 10.1093/jac/14.suppl_b.59
DO - 10.1093/jac/14.suppl_b.59
M3 - Article
C2 - 6501135
AN - SCOPUS:0021605390
SN - 0305-7453
VL - 14
SP - 59
EP - 65
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - SUPPL. B
ER -