Surveillance for Differentiated Thyroid Cancer Recurrence

Research output: Contribution to journalReview article

Abstract

Serum thyroglobulin monitoring along with anatomic and functional imaging play key roles in the surveillance of patients with differentiated thyroid cancer after initial treatment. Among patients with a disease stage justifying thyroid remnant ablation or with suspected metastatic disease, radioiodine whole-body scans are essential in the months after surgery. For patients with low to moderate-risk cancers, ultrasonography of the neck (with measurement of serum thyroglobulin on thyroid hormone replacement) are the best initial diagnostic modalities, and are often the only tests required. In individuals suspected of having distant metastases, CT, MRI, and 18F-FDG PET can make important contributions in localizing residual disease and monitoring its progression and responses to therapy, provided they are used in the appropriate setting.

Original languageEnglish (US)
Pages (from-to)239-252
Number of pages14
JournalEndocrinology and Metabolism Clinics of North America
Volume48
Issue number1
DOIs
StatePublished - Mar 1 2019

Fingerprint

Thyroid Neoplasms
Thyroglobulin
Recurrence
Whole Body Imaging
Fluorodeoxyglucose F18
Head and Neck Neoplasms
Serum
Thyroid Hormones
Ultrasonography
Thyroid Gland
Neoplasm Metastasis
Therapeutics

Keywords

  • Cancer recurrence
  • Differentiated thyroid cancer
  • Serum thyroglobulin monitoring
  • Thyroid cancer imaging

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Surveillance for Differentiated Thyroid Cancer Recurrence. / Santhanam, Prasanna; Ladenson, Paul W.

In: Endocrinology and Metabolism Clinics of North America, Vol. 48, No. 1, 01.03.2019, p. 239-252.

Research output: Contribution to journalReview article

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