TY - JOUR
T1 - Surgical Therapy for Small-Bowel Carcinoid Tumors
AU - Strodel, William E.
AU - Talpos, Gary
AU - Eckhauser, Frederic
AU - Thompson, Norman
PY - 1983/4
Y1 - 1983/4
N2 - Eighty-two symptomatic patients with carcinoid tumors of the small intestine were examined and treated over a 20-year period. Common clinical features included weight loss, diarrhea, and symptoms of intermittent bowel obstruction; 25 patients (30%) exhibited the carcinoid syndrome. Multiple carcinoid tumors occurred in 23 patients (28%), and hepatic metastases were present in 30 (37%). All patients underwent operation. The overall mortality was 7%, and the cumulative five-year survival rate was 59%. Two factors influenced prognosis after operation: hepatic metastases and incomplete resection. Other variables, including the sex and age of the patient and the size of the primary tumor, were of no additional prognostic value. Wide resection of the tumor, including regional lymph nodes, is indicated, regardless of the size of the primary tumor.
AB - Eighty-two symptomatic patients with carcinoid tumors of the small intestine were examined and treated over a 20-year period. Common clinical features included weight loss, diarrhea, and symptoms of intermittent bowel obstruction; 25 patients (30%) exhibited the carcinoid syndrome. Multiple carcinoid tumors occurred in 23 patients (28%), and hepatic metastases were present in 30 (37%). All patients underwent operation. The overall mortality was 7%, and the cumulative five-year survival rate was 59%. Two factors influenced prognosis after operation: hepatic metastases and incomplete resection. Other variables, including the sex and age of the patient and the size of the primary tumor, were of no additional prognostic value. Wide resection of the tumor, including regional lymph nodes, is indicated, regardless of the size of the primary tumor.
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U2 - 10.1001/archsurg.1983.01390040003001
DO - 10.1001/archsurg.1983.01390040003001
M3 - Article
C2 - 6830429
AN - SCOPUS:0020622520
VL - 118
SP - 391
EP - 397
JO - JAMA Surgery
JF - JAMA Surgery
SN - 2168-6254
IS - 4
ER -