Surgical management of primary and metastatic spinal tumors

Paul E. Kaloostian, Patricia L. Zadnik, Arnold B. Etame, Frank D. Vrionis, Ziya L. Gokaslan, Daniel Sciubba

Research output: Contribution to journalArticle

Abstract

Background: The axial skeleton is a common site for primary tumors and metastatic disease, with metastatic disease being much more common. Primary and metastatic spinal tumors have a diverse range of aggressiveness, ranging from benign lesions to highly infiltrative malignant tumors. Methods: The authors reviewed the results of articles describing the treatment and outcomes of patients with metastatic disease or primary tumors of the spinal column. Results: En bloc resection is the mainstay of treatment for malignant primary tumors of the spinal column. Intralesional resection is generally appropriate for benign primary tumors. Low-quality evidence supports the use of chemotherapy in select primary tumors; however, radiation therapy is often used for incompletely resected or unresectable lesions. Surgical considerations for the treatment of metastatic disease are more nuanced and require that the health care professional consider patient performance status and the pathology of the primary tumor. Conclusions: The treatment of metastatic and primary tumors of the spinal column requires a multidisciplinary approach in order to offer patients the best opportunity for long-term survival.

Original languageEnglish (US)
Pages (from-to)133-139
Number of pages7
JournalCancer Control
Volume21
Issue number2
StatePublished - 2014

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Neoplasms
Spine
Skeleton
Radiotherapy
Therapeutics
Pathology
Delivery of Health Care
Drug Therapy
Survival

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Medicine(all)

Cite this

Kaloostian, P. E., Zadnik, P. L., Etame, A. B., Vrionis, F. D., Gokaslan, Z. L., & Sciubba, D. (2014). Surgical management of primary and metastatic spinal tumors. Cancer Control, 21(2), 133-139.

Surgical management of primary and metastatic spinal tumors. / Kaloostian, Paul E.; Zadnik, Patricia L.; Etame, Arnold B.; Vrionis, Frank D.; Gokaslan, Ziya L.; Sciubba, Daniel.

In: Cancer Control, Vol. 21, No. 2, 2014, p. 133-139.

Research output: Contribution to journalArticle

Kaloostian, PE, Zadnik, PL, Etame, AB, Vrionis, FD, Gokaslan, ZL & Sciubba, D 2014, 'Surgical management of primary and metastatic spinal tumors', Cancer Control, vol. 21, no. 2, pp. 133-139.
Kaloostian PE, Zadnik PL, Etame AB, Vrionis FD, Gokaslan ZL, Sciubba D. Surgical management of primary and metastatic spinal tumors. Cancer Control. 2014;21(2):133-139.
Kaloostian, Paul E. ; Zadnik, Patricia L. ; Etame, Arnold B. ; Vrionis, Frank D. ; Gokaslan, Ziya L. ; Sciubba, Daniel. / Surgical management of primary and metastatic spinal tumors. In: Cancer Control. 2014 ; Vol. 21, No. 2. pp. 133-139.
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