Surgical Management of End-Stage Achalasia

Daniela Molena, Stephen C Yang

Research output: Contribution to journalArticle

Abstract

Esophageal achalasia is a chronic and progressive motility disorder that leads to massive esophageal dilation when left untreated. Treatment for achalasia is palliative and aimed to relieve the outflow obstruction at the level of the lower esophageal sphincter, yet protecting the esophageal mucosa from refluxing gastric acids. The best way to accomplish this goal is through an esophageal myotomy and partial fundoplication, with a success rate >90%. Progression of disease, treatment failure, and complications from gastroesophageal reflux disease cause progressive deterioration of the esophageal function to an end stage in about 5% of patients. The only chance to improve symptoms in this small group of patients is through an esophageal resection. This article will review the indications for esophagectomy in end-stage achalasia, present the different types of surgical approach and possibilities for reconstruction of the alimentary tract, and summarize the short-term and long-term postoperative results.

Original languageEnglish (US)
Pages (from-to)19-26
Number of pages8
JournalSeminars in Thoracic and Cardiovascular Surgery
Volume24
Issue number1
DOIs
StatePublished - 2012

Fingerprint

Esophageal Achalasia
Fundoplication
Lower Esophageal Sphincter
Esophagectomy
Gastric Acid
Gastroesophageal Reflux
Treatment Failure
Disease Progression
Dilatation
Therapeutics

Keywords

  • Achalasia
  • End-stage
  • Esophageal replacement
  • Esophagectomy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Surgical Management of End-Stage Achalasia. / Molena, Daniela; Yang, Stephen C.

In: Seminars in Thoracic and Cardiovascular Surgery, Vol. 24, No. 1, 2012, p. 19-26.

Research output: Contribution to journalArticle

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