Surgical management of craniofacial neurofibromatosis type 1 associated tumors

Lindsay E. Janes, Jennifer Sabino, Jamil A. Matthews, John C. Papadimitriou, Scott E. Strome, Devinder P. Singh

Research output: Contribution to journalArticlepeer-review

Abstract

Neurofibromatosis type 1 is a rare, autosomal dominant disorder than can present with varying degrees of disfigurement depending on the associated tumor extent and location. Surgical resection is considered the most effective management of these typically benign tumors, indicated when symptoms include pain, extreme deformity, or interference with normal physical function. Giant tumors of the craniofacial region present particular difficulty due to the size of the post-resection wound deficit and the high risk surgery poses to function such as vision and facial animation in this region. Strategies of management are discussed.

Original languageEnglish (US)
Pages (from-to)1273-1277
Number of pages5
JournalJournal of Craniofacial Surgery
Volume24
Issue number4
DOIs
StatePublished - Jul 1 2013

Keywords

  • Neurofibromatosis
  • craniofacial
  • free flap

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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