Surgical indications and optimization of patients for resectable esophageal malignancies

Joshua C. Grimm, Vicente Valero, Daniela Molena

Research output: Contribution to journalArticlepeer-review

Abstract

Esophageal cancer is a devastating diagnosis with very dire long-term survival rates. This is largely due to its rather insidious progression, which leads to most patients being diagnosed with advanced disease. Recently, however, a greater understanding of the pathogenesis of esophageal malignancies has afforded surgeons and oncologists with new opportunities for intervention and management. Coupled with improvements in imaging, staging, and medical therapies, surgeons have continued to enhance their knowledge of the nuances of esophageal resection, which has resulted in the development of minimally invasive approaches with similar overall oncologic outcomes. This marriage of more efficacious induction therapy and diminished morbidity after esophagectomy offers new promise to patients diagnosed with this aggressive form of cancer. The following review will highlight these most recent advances and will offer insight into our own approach to patients with resectable esophageal malignancy.

Original languageEnglish (US)
Pages (from-to)249-257
Number of pages9
JournalJournal of Thoracic Disease
Volume6
Issue number3
DOIs
StatePublished - 2014

Keywords

  • Esophageal cancer
  • Indication for surgery
  • Preoperative optimization
  • Review

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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