Surgery for oligometastasis of pancreatic cancer

Fengchun Lu, Katherine E. Poruk, Matthew J. Weiss

Research output: Contribution to journalReview articlepeer-review

Abstract

The incidence of pancreatic adenocarcinoma (PDAC) has steadily increased over the past several decades. The majority of PDAC patients will present with distant metastases, limiting surgical management in this population. Hepatectomy and pulmonary metastasectomy (PM) has been well established for colorectal cancer patients with isolated, resectable hepatic or pulmonary metastatic disease. Recent advancements in effective systemic therapy for PDAC have led to the selection of certain patients where metastectomy may be potentially indicated. However, the indication for resection of oligometastases in PDAC is not well defined. This review will discuss the current literature on the surgical management of metastatic disease for PDAC with a specific focus on surgical resection for isolated hepatic and pulmonary metastases.

Original languageEnglish (US)
Pages (from-to)358-367
Number of pages10
JournalChinese Journal of Cancer Research
Volume27
Issue number4
DOIs
StatePublished - Jan 1 2015

Keywords

  • Hepatic metastasis
  • Oligometastasis
  • Pancreatic cancer (PC)
  • Pulmonary metastasis
  • Surgical management

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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