Surfaces and Orientations: Much to FRET about?

Ivan Rasnik; Sean A. McKinney; Taekjip Ha

doi:10.1021/ar040138c

Surfaces and Orientations: Much to FRET about?

Ivan Rasnik, Sean A. McKinney, Taekjip Ha

Research output: Contribution to journal › Article › peer-review

119 Scopus citations

Abstract

Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this Account, we examine different techniques of extending observation times via immobilization and illustrate how useful biological information can be obtained from single molecule FRET time trajectories with or without absolute distance information.

Original language	English (US)
Pages (from-to)	542-548
Number of pages	7
Journal	Accounts of chemical research
Volume	38
Issue number	7
DOIs	https://doi.org/10.1021/ar040138c
State	Published - Jul 2005
Externally published	Yes

ASJC Scopus subject areas

General Chemistry

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10.1021/ar040138c

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title = "Surfaces and Orientations: Much to FRET about?",

abstract = "Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this Account, we examine different techniques of extending observation times via immobilization and illustrate how useful biological information can be obtained from single molecule FRET time trajectories with or without absolute distance information.",

author = "Ivan Rasnik and McKinney, {Sean A.} and Taekjip Ha",

year = "2005",

month = jul,

doi = "10.1021/ar040138c",

language = "English (US)",

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pages = "542--548",

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issn = "0001-4842",

publisher = "American Chemical Society",

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T1 - Surfaces and Orientations

T2 - Much to FRET about?

AU - Rasnik, Ivan

AU - McKinney, Sean A.

AU - Ha, Taekjip

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Y1 - 2005/7

N2 - Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this Account, we examine different techniques of extending observation times via immobilization and illustrate how useful biological information can be obtained from single molecule FRET time trajectories with or without absolute distance information.

AB - Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this Account, we examine different techniques of extending observation times via immobilization and illustrate how useful biological information can be obtained from single molecule FRET time trajectories with or without absolute distance information.

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U2 - 10.1021/ar040138c

DO - 10.1021/ar040138c

M3 - Article

C2 - 16028888

AN - SCOPUS:23744433971

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VL - 38

SP - 542

EP - 548

JO - Accounts of chemical research

JF - Accounts of chemical research

IS - 7

ER -

Surfaces and Orientations: Much to FRET about?

Abstract

ASJC Scopus subject areas

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