Surface antigens of normal early embryos and a tumor model system useful for their further study

The authors review experiments on the presence of strong transplantation antigens, H 2 antigens, in mouse gametes and early embryos. Parallels are drawn between antigenic structure of embryos and tumour cells, and experiments with a model tumour system, a teratoma, are presented indicating the presence in early embryos of surface antigens which are shared with the tumour.