Suppression of Lymphocyte Function After Aortic Reconstruction: Use of Nonimmunosuppressive Anesthesia

Raphael M. Keane, Andrew M. Munster, William Birmingham, Richard A. Winchurch, Thomas R. Gadacz, Calvin B. Ernst

Research output: Contribution to journalArticlepeer-review

Abstract

Serial estimations of lymphocyte responses to antigens and mitogens and in mixed lymphocyte culture in 13 major vascular surgical patients were carried out before and after operation, which was performed using anesthetic agents that have been shown not to depress lymphocyte function. All responses were significantly depressed up to five to eight days, and some up to nine to 11 days. Such depression, attributable to surgical trauma, may underline the vulnerability to infection of these patients who are having prostheses inserted.

Original languageEnglish (US)
Pages (from-to)1133-1135
Number of pages3
JournalArchives of surgery
Volume117
Issue number9
DOIs
StatePublished - Sep 1982

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Suppression of Lymphocyte Function After Aortic Reconstruction: Use of Nonimmunosuppressive Anesthesia'. Together they form a unique fingerprint.

Cite this