Suppression of hay fever symptoms with intranasal dexamethasone aerosol

Philip S. Norman; Walter L. Winkenwerder

doi:10.1016/0021-8707(65)90087-0

Suppression of hay fever symptoms with intranasal dexamethasone aerosol

Philip S. Norman, Walter L. Winkenwerder

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34 Scopus citations

Abstract

Dexamethasone phosphate aerosol was tried intranasally in a dose of 1 mg. daily in 40 patients with seasonal ragweed hay fever, with the use of a double blind crossover plan of study. By three methods of evaluation applied independently, significant improvement of hay fever symptoms was obtained in about 75 per cent of patients. No steroid side effects were observed; some patients complained of nasal irritation immediately after spraying.

Original language	English (US)
Pages (from-to)	284-292
Number of pages	9
Journal	Journal of Allergy
Volume	36
Issue number	3
DOIs	https://doi.org/10.1016/0021-8707(65)90087-0
State	Published - 1965
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Suppression of hay fever symptoms with intranasal dexamethasone aerosol",

abstract = "Dexamethasone phosphate aerosol was tried intranasally in a dose of 1 mg. daily in 40 patients with seasonal ragweed hay fever, with the use of a double blind crossover plan of study. By three methods of evaluation applied independently, significant improvement of hay fever symptoms was obtained in about 75 per cent of patients. No steroid side effects were observed; some patients complained of nasal irritation immediately after spraying.",

author = "Norman, {Philip S.} and Winkenwerder, {Walter L.}",

note = "Funding Information: Division Allrrgy autl Iufrctious Univcrsit,y and Hospital. for publication July 14, 1964. by a grant from Merck Sharp & Dohmr Career Dewlopmmt Awarder , Sational Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

year = "1965",

doi = "10.1016/0021-8707(65)90087-0",

language = "English (US)",

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journal = "Journal of Allergy",

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AU - Norman, Philip S.

AU - Winkenwerder, Walter L.

N1 - Funding Information: Division Allrrgy autl Iufrctious Univcrsit,y and Hospital. for publication July 14, 1964. by a grant from Merck Sharp & Dohmr Career Dewlopmmt Awarder , Sational Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 1965

Y1 - 1965

N2 - Dexamethasone phosphate aerosol was tried intranasally in a dose of 1 mg. daily in 40 patients with seasonal ragweed hay fever, with the use of a double blind crossover plan of study. By three methods of evaluation applied independently, significant improvement of hay fever symptoms was obtained in about 75 per cent of patients. No steroid side effects were observed; some patients complained of nasal irritation immediately after spraying.

AB - Dexamethasone phosphate aerosol was tried intranasally in a dose of 1 mg. daily in 40 patients with seasonal ragweed hay fever, with the use of a double blind crossover plan of study. By three methods of evaluation applied independently, significant improvement of hay fever symptoms was obtained in about 75 per cent of patients. No steroid side effects were observed; some patients complained of nasal irritation immediately after spraying.

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Suppression of hay fever symptoms with intranasal dexamethasone aerosol

Abstract

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