TY - JOUR
T1 - Supply, use, and abuse of intravenous immunoglobulin
AU - Nowak-Wegrzyn, Anna
AU - Lederman, Howard M.
PY - 1999
Y1 - 1999
N2 - Intravenous immunoglobulin is used as a replacement therapy in primary immunodeficiency diseases as well as an immunomodulatory agent in a variety of autoimmune and inflammatory disorders. The mechanisms of intravenous immunoglobulin action are complex and, for some disorders, not well understood. This paper reviews the recent literature and discusses approved, new, and controversial indications for intravenous immunoglobulin therapy, with special emphasis on its mechanism of action.
AB - Intravenous immunoglobulin is used as a replacement therapy in primary immunodeficiency diseases as well as an immunomodulatory agent in a variety of autoimmune and inflammatory disorders. The mechanisms of intravenous immunoglobulin action are complex and, for some disorders, not well understood. This paper reviews the recent literature and discusses approved, new, and controversial indications for intravenous immunoglobulin therapy, with special emphasis on its mechanism of action.
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U2 - 10.1097/00008480-199912000-00011
DO - 10.1097/00008480-199912000-00011
M3 - Article
C2 - 10590912
AN - SCOPUS:0032705402
SN - 1040-8703
VL - 11
SP - 533
EP - 539
JO - Current opinion in pediatrics
JF - Current opinion in pediatrics
IS - 6
ER -