1H and 13C NMR assignments of the antitumor macrolide bryostatin 1

Daniel E. Schaufelberger; Gwendolyn N. Chmurny; Mary P. Koleck

doi:10.1002/mrc.1260290414

¹H and ¹³C NMR assignments of the antitumor macrolide bryostatin 1

Daniel E. Schaufelberger, Gwendolyn N. Chmurny, Mary P. Koleck

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

During a large‐scale isolation of bryostatin 1, NMR measurements indicated that parts of the published ¹³C and ¹H NMR assignments had to be revised. These reassignments were based on extensive homonuclear and heteronuclear one‐ and two‐dimensional NMR techniques performed at 500 MHz. These independently obtained assignments are also in good agreement with the revised assignments and structure of bryostatin 3.

Original language	English (US)
Pages (from-to)	366-374
Number of pages	9
Journal	Magnetic Resonance in Chemistry
Volume	29
Issue number	4
DOIs	https://doi.org/10.1002/mrc.1260290414
State	Published - Apr 1991
Externally published	Yes

Keywords

Bryostatin 1
NMR data
Structure

ASJC Scopus subject areas

General Chemistry
General Materials Science

Access to Document

10.1002/mrc.1260290414

Cite this

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title = "1H and 13C NMR assignments of the antitumor macrolide bryostatin 1",

abstract = "During a large‐scale isolation of bryostatin 1, NMR measurements indicated that parts of the published 13C and 1H NMR assignments had to be revised. These reassignments were based on extensive homonuclear and heteronuclear one‐ and two‐dimensional NMR techniques performed at 500 MHz. These independently obtained assignments are also in good agreement with the revised assignments and structure of bryostatin 3.",

keywords = "Bryostatin 1, NMR data, Structure",

author = "Schaufelberger, {Daniel E.} and Chmurny, {Gwendolyn N.} and Koleck, {Mary P.}",

year = "1991",

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volume = "29",

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journal = "Magnetic Resonance in Chemistry",

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T1 - 1H and 13C NMR assignments of the antitumor macrolide bryostatin 1

AU - Schaufelberger, Daniel E.

AU - Chmurny, Gwendolyn N.

AU - Koleck, Mary P.

PY - 1991/4

Y1 - 1991/4

N2 - During a large‐scale isolation of bryostatin 1, NMR measurements indicated that parts of the published 13C and 1H NMR assignments had to be revised. These reassignments were based on extensive homonuclear and heteronuclear one‐ and two‐dimensional NMR techniques performed at 500 MHz. These independently obtained assignments are also in good agreement with the revised assignments and structure of bryostatin 3.

AB - During a large‐scale isolation of bryostatin 1, NMR measurements indicated that parts of the published 13C and 1H NMR assignments had to be revised. These reassignments were based on extensive homonuclear and heteronuclear one‐ and two‐dimensional NMR techniques performed at 500 MHz. These independently obtained assignments are also in good agreement with the revised assignments and structure of bryostatin 3.

KW - Bryostatin 1

KW - NMR data

KW - Structure

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DO - 10.1002/mrc.1260290414

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