18F-flourodeoxy-glucose PET/computed tomography in brain tumors: Value to patient management and survival outcomes

Rick Wray, Lilja Solnes, Esther Mena, Avner Meoded, Rathan M Subramaniam

Research output: Contribution to journalReview article

Abstract

18F-flourodeoxy-glucose (FDG) PET/computed tomography (CT) is most useful in the evaluation of primary central nervous system (CNS) lymphoma, important in diagnosis, pretherapy prognosis, and therapy response evaluation. Utility in working up gliomas is less effective, and FDG PET/CT is most helpful when MR imaging is unclear. FDG avidity correlates with the grade of gliomas. FDG PET/CT can be used to noninvasively identify malignant transformation. Establishing this change in the disease process has significant effects on patient management and survival outcome.

Original languageEnglish (US)
Pages (from-to)423-430
Number of pages8
JournalPET Clinics
Volume10
Issue number3
DOIs
StatePublished - Jul 1 2015

Keywords

  • Brain
  • Cancer
  • Central nervous system neoplasm
  • PET
  • PET/computed tomography
  • Patient management
  • Survival outcomes
  • Tumor

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging

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