TY - JOUR
T1 - SUMmOning Daxx-Mediated Repression
AU - Mukhopadhyay, Debaditya
AU - Matunis, Michael J.
PY - 2011/4/8
Y1 - 2011/4/8
N2 - An intimate relationship exists between the transcriptional coregulator Daxx, SUMO, and PML nuclear bodies. In this issue, Chang et al. (2011) provide structural insights into how phosphorylation of Daxx increases its affinity toward SUMOs and functional insights into how enhanced SUMO binding affects Daxx-PML interactions, PML nuclear body localization, and Daxx-mediated repression of genes encoding for antiapoptotic factors.
AB - An intimate relationship exists between the transcriptional coregulator Daxx, SUMO, and PML nuclear bodies. In this issue, Chang et al. (2011) provide structural insights into how phosphorylation of Daxx increases its affinity toward SUMOs and functional insights into how enhanced SUMO binding affects Daxx-PML interactions, PML nuclear body localization, and Daxx-mediated repression of genes encoding for antiapoptotic factors.
UR - http://www.scopus.com/inward/record.url?scp=79953304467&partnerID=8YFLogxK
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U2 - 10.1016/j.molcel.2011.03.008
DO - 10.1016/j.molcel.2011.03.008
M3 - Short survey
C2 - 21474063
AN - SCOPUS:79953304467
SN - 1097-2765
VL - 42
SP - 4
EP - 5
JO - Molecular cell
JF - Molecular cell
IS - 1
ER -