TY - JOUR
T1 - Sudden death related cardiomyopathies - Hypertrophic cardiomyopathy
AU - Goff, Zackary D.
AU - Calkins, Hugh
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Hypertrophic cardiomyopathy (HCM) is a form of inherited cardiomyopathy. Most individuals with HCM experience minimal symptoms throughout their lifetime. However, those with HCM are at risk of ventricular arrhythmias and sudden cardiac death (SCD), the most feared complication of HCM. Implantable cardioverter defibrillator (ICD) implantation has played a large role in transforming this disease from one with an ominous prognosis to one with mortality rates that are on par with the general public. Since the early 2000s, balance between SCD prevention and unnecessary ICD placement has been sought, this is reflected in the evolution of SCD risk stratification models for patients with HCM. This review discusses key concepts pertaining to HCM, with emphasis on prevention of SCD, and summarizes and compares the recommendations for ICD implantation in current guidelines.
AB - Hypertrophic cardiomyopathy (HCM) is a form of inherited cardiomyopathy. Most individuals with HCM experience minimal symptoms throughout their lifetime. However, those with HCM are at risk of ventricular arrhythmias and sudden cardiac death (SCD), the most feared complication of HCM. Implantable cardioverter defibrillator (ICD) implantation has played a large role in transforming this disease from one with an ominous prognosis to one with mortality rates that are on par with the general public. Since the early 2000s, balance between SCD prevention and unnecessary ICD placement has been sought, this is reflected in the evolution of SCD risk stratification models for patients with HCM. This review discusses key concepts pertaining to HCM, with emphasis on prevention of SCD, and summarizes and compares the recommendations for ICD implantation in current guidelines.
KW - Cardiomyopathy
KW - Hypertrophic cardiomyopathy
KW - Sudden cardiac death
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U2 - 10.1016/j.pcad.2019.04.001
DO - 10.1016/j.pcad.2019.04.001
M3 - Review article
C2 - 31004609
AN - SCOPUS:85064813056
SN - 0033-0620
VL - 62
SP - 212
EP - 216
JO - Progress in Cardiovascular Diseases
JF - Progress in Cardiovascular Diseases
IS - 3
ER -