Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support

W. Rabitsch, T. Staudinger, S. A. Brugger, E. Reiter, F. Keil, C. Herold, K. Lechner, H. T. Greinix, P. Kalhs

Research output: Contribution to journalArticlepeer-review

Abstract

A 34-year-old man suffering from Hodgkin's disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days. High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation. High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.

Original languageEnglish (US)
Pages (from-to)1067-1069
Number of pages3
JournalBone marrow transplantation
Volume21
Issue number10
DOIs
StatePublished - May 2 1998

Keywords

  • ARDS
  • CPAP
  • High-dose chemotherapy and peripheral blood progenitor cell rescue
  • Non-invasive ventilation
  • Non-invasive ventilatory support

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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