Abstract
A 34-year-old man suffering from Hodgkin's disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days. High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation. High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.
Original language | English (US) |
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Pages (from-to) | 1067-1069 |
Number of pages | 3 |
Journal | Bone marrow transplantation |
Volume | 21 |
Issue number | 10 |
DOIs | |
State | Published - May 2 1998 |
Externally published | Yes |
Keywords
- ARDS
- CPAP
- High-dose chemotherapy and peripheral blood progenitor cell rescue
- Non-invasive ventilation
- Non-invasive ventilatory support
ASJC Scopus subject areas
- Hematology
- Transplantation